BillionToOne, Inc. reported Q4 and full year 2025 financial results with total revenue of $96.1 million and $305.1 million respectively, achieving operating income of $10.3 million and $16.0 million, and raised 2026 revenue guidance to $430-$445 million. The Board approved the BillionToOne Annual Incentive Plan effective for performance periods beginning January 1, 2026.
Key takeaways
Total Q4 2025 revenue $96.1 million, up 113% from $45.1 million in Q4 2024
Full year 2025 revenue $305.1 million, up 100% from $152.6 million in 2024
Q4 2025 operating income $10.3 million vs operating loss $11.7 million in Q4 2024
Full year 2025 operating income $16.0 million vs operating loss $47.1 million in 2024
Raised 2026 revenue guidance to $430-$445 million, expects positive operating income
Approved BillionToOne Annual Incentive Plan effective January 1, 2026 for executives and employees